<p dir="ltr">The research was designed to answer the following questions:</p><p dir="ltr">I. What is the attitude of the respondents towards rabies disease?</p><p dir="ltr">II. How knowledgeable are the respondents towards rabies?</p><p dir="ltr">III. What practices with potential to help prevent outbreaks of rabies have the respondents adopted?</p><p dir="ltr">A cross-sectional questionnaire-based survey was conducted to collect the data from a randomly selected sample of respondents from two areas namely, Embo (a rural area) and Verulam (an urban area), in KwaZulu-Natal Province, South Africa. The data shows low levels of knowledge of rabies among the respondents. In addition, although, in some respects, the respondents displayed a good attitude towards rabies, the data shows that there is room for improvement. Finally the data was able to demonstrate the socio-demographic characteristics that are significantly correlated with a high knowledge score among the respondents. The high prevalence of poor practices with respect to rabies, suggests that the target population is vulnerable to rabies outbreaks.</p>